About
The Echo 525 Acoustic Liquid Handler is a non-contact, acoustic droplet ejection (ADE) instrument capable of transferring nanoliter to microliter volumes of liquid with high precision and minimal waste. Unlike traditional pipette-based liquid handlers, the Echo 525 uses focused acoustic energy to eject droplets as small as 2.5 nL directly from a source plate to a destination plate without tips. This eliminates cross-contamination, reduces reagent consumption, and enables highly flexible compound and assay dispensing. It is compatible with a wide range of plate formats (384-well, 1536-well) and is controlled by the Echo Liquid Handler Software.

User Notes

• Wipe off and decontaminate equipment surfaces and source/destination plates with 70% ethanol before and after use. Do not use bleach.
• Ensure source plates are filled to the recommended minimum volume to allow acoustic ejection (typically ≥ 6 µL per well for 384-well LDV plates).
• Inspect source plates for bubbles or particulates before loading as these can interfere with droplet ejection.

User manual: echo_525_manual.pdf
Consumables: echo_acoustic_liquid_handler_consumables_brochure.pdf
Plate audit applications: plate_audit.pdf