====== Thermo Scientific Orbitrap Ascend™ MultiOmics Tribrid™ Mass Spectrometer ======

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**About**\\
The Thermo Scientific Orbitrap Ascend™ MultiOmics Tribrid™ Mass Spectrometer is a state-of-the-art high-resolution accurate-mass (HRAM) LC-MS/MS system built on the revolutionary **Tribrid™ architecture** — a quadrupole mass filter, dual-pressure linear ion trap, and ultra-high-field Orbitrap mass analyzer operating in tandem. The MultiOmics Edition is specifically configured for maximum coverage and versatility across proteomics, metabolomics, lipidomics, glycoproteomics, and glycomics workflows. It achieves Orbitrap resolution up to **480,000 FWHM** at m/z 200, mass accuracy better than **<1 ppm RMS** with internal calibration, DDA MS/MS acquisition rates up to **45 Hz**, and femtogram-level sensitivity. The instrument features **Active Ion Management (AIM+)** technology, **Dual Ion Routing Multipoles (IRMs)**, a high-capacity transfer tube, and an electrodynamic ion funnel for exceptional ion transmission across a broad mass range. Multiple orthogonal fragmentation techniques — CID, HCD, ETD, EThcD, ETciD, UVPD — are available at any MSn stage. Intelligent acquisition tools including **Real-Time Search (RTS)**, **Real-Time Library Search (RTLS)**, and **AcquireX** automate experimental decision-making to maximize sample throughput, proteome coverage, and data quality. The **Auto-Ready ion source** enables fully automated, unattended mass calibration without manual hardware reconfiguration. The instrument is controlled with **Thermo Scientific Xcalibur™** software and supports downstream analysis in **Proteome Discoverer™**, **Compound Discoverer™**, **BioPharma Finder™**, and **ProSightPC™**.