====== Beckman Coulter Echo 525 Liquid Handler ======

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**About**\\
The Echo 525 Acoustic Liquid Handler is a non-contact, acoustic droplet ejection (ADE) instrument capable of transferring nanoliter to microliter volumes of liquid with high precision and minimal waste. Unlike traditional pipette-based liquid handlers, the Echo 525 uses focused acoustic energy to eject droplets as small as 2.5 nL directly from a source plate to a destination plate without tips. This eliminates cross-contamination, reduces reagent consumption, and enables highly flexible compound and assay dispensing. It is compatible with a wide range of plate formats (384-well, 1536-well) and is controlled by the **Echo Liquid Handler Software**.

**User Notes**

  * Wipe off and decontaminate equipment surfaces and source/destination plates with 70% ethanol before and after use. **Do not use bleach.**
  * Ensure source plates are filled to the recommended minimum volume to allow acoustic ejection (typically ≥ 6 µL per well for 384-well LDV plates).
  * Inspect source plates for bubbles or particulates before loading as these can interfere with droplet ejection.

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====== Reference Documentation ======
User manual: {{ :echo_525_manual.pdf |}}\\
Consumables: {{ :echo_acoustic_liquid_handler_consumables_brochure.pdf |}}\\
Plate audit applications: {{ :plate_audit.pdf |}}